Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Scgb1a1  secretoglobin, family 1A, member 1   (Synonyms: Blastokinin, CC10, CC16, CCSP, club cell secretory protein, PCB-BP, UG, Utg)
Results	Reference
1*	J:104973 Besnard V, Wert SE, Kaestner KH, Whitsett JA, Stage-specific regulation of respiratory epithelial cell differentiation by Foxa1. Am J Physiol Lung Cell Mol Physiol. 2005 Nov;289(5):L750-9
1	J:276488 Bilodeau M, Shojaie S, Ackerley C, Post M, Rossant J, Identification of a proximal progenitor population from murine fetal lungs with clonogenic and multilineage differentiation potential. Stem Cell Reports. 2014 Oct 14;3(4):634-49
1*	J:147561 Blatt EN, Yan XH, Wuerffel MK, Hamilos DL, Brody SL, Forkhead transcription factor HFH-4 expression is temporally related to ciliogenesis. Am J Respir Cell Mol Biol. 1999 Aug;21(2):168-76
1	J:185338 Boucherat O, Chakir J, Jeannotte L, The loss of Hoxa5 function promotes Notch-dependent goblet cell metaplasia in lung airways. Biol Open. 2012;q:677-691
1	J:202792 Boucherat O, Montaron S, Berube-Simard FA, Aubin J, Philippidou P, Wellik DM, Dasen JS, Jeannotte L, Partial functional redundancy between Hoxa5 and Hoxb5 paralog genes during lung morphogenesis. Am J Physiol Lung Cell Mol Physiol. 2013 Jun 15;304(12):L817-30
1	J:229471 Branchfield K, Nantie L, Verheyden JM, Sui P, Wienhold MD, Sun X, Pulmonary neuroendocrine cells function as airway sensors to control lung immune response. Science. 2016 Feb 12;351(6274):707-10
1	J:197340 Chung C, Kim T, Kim M, Kim M, Song H, Kim TS, Seo E, Lee SH, Kim H, Kim SK, Yoo G, Lee DH, Hwang DS, Kinashi T, Kim JM, Lim DS, Hippo-Foxa2 signaling pathway plays a role in peripheral lung maturation and surfactant homeostasis. Proc Natl Acad Sci U S A. 2013 May 7;110(19):7732-7
1*	J:78151 Clark K, Hammond E, Rabbitts P, Temporal and spatial expression of two isoforms of the Dutt1/Robo1 gene in mouse development. FEBS Lett. 2002 Jul 17;523(1-3):12-6
1	J:91818 Collins BJ, Kleeberger W, Ball DW, Notch in lung development and lung cancer. Semin Cancer Biol. 2004 Oct;14(5):357-64
1	J:343443 Cooney RA, Saal ML, Geraci KP, Maynard C, Cleaver O, Hoang ON, Moore TT, Hwang RF, Axelrod JD, Vladar EK, A WNT4- and DKK3-driven canonical to noncanonical Wnt signaling switch controls multiciliogenesis. J Cell Sci. 2023 Aug 15;136(16)
1	J:241179 Duquesnes N, Callot C, Jeannot P, Daburon V, Nakayama KI, Manenti S, Davy A, Besson A, p57(Kip2) knock-in mouse reveals CDK-independent contribution in the development of Beckwith-Wiedemann syndrome. J Pathol. 2016 Jul;239(3):250-61
1	J:106392 Eblaghie MC, Reedy M, Oliver T, Mishina Y, Hogan BL, Evidence that autocrine signaling through Bmpr1a regulates the proliferation, survival and morphogenetic behavior of distal lung epithelial cells. Dev Biol. 2006 Mar 1;291(1):67-82
1*	J:105164 Fernandez-Valdivia R, Zhang Y, Pai S, Metzker ML, Schumacher A, l7Rn6 Encodes a Novel Protein Required for Clara Cell Function in Mouse Lung Development. Genetics. 2006 Jan;172(1):389-99
1	J:293435 Fuentes-Mateos R, Jimeno D, Gomez C, Calzada N, Fernandez-Medarde A, Santos E, Concomitant deletion of HRAS and NRAS leads to pulmonary immaturity, respiratory failure and neonatal death in mice. Cell Death Dis. 2019 Nov 4;10(11):838
1	J:247780 Fujimoto J, Nunomura-Nakamura S, Liu Y, Lang W, McDowell T, Jakubek Y, Ezzeddine D, Kapere Ochieng J, Petersen J, Davies G, Fukuoka J, Wistuba II, Ehli E, Fowler J, Scheet P, Kadara H, Development of Kras mutant lung adenocarcinoma in mice with knockout of the airway lineage-specific gene Gprc5a. Int J Cancer. 2017 Oct 15;141(8):1589-1599
1	J:220467 Galvis LA, Holik AZ, Short KM, Pasquet J, Lun AT, Blewitt ME, Smyth IM, Ritchie ME, Asselin-Labat ML, Repression of Igf1 expression by Ezh2 prevents basal cell differentiation in the developing lung. Development. 2015 Apr 15;142(8):1458-69
1	J:315450 Giridhar PV, Bell SM, Sridharan A, Rajavelu P, Kitzmiller JA, Na CL, Kofron M, Brandt EB, Ericksen M, Naren AP, Moon C, Khurana Hershey GK, Whitsett JA, Airway Epithelial KIF3A Regulates Th2 Responses to Aeroallergens. J Immunol. 2016 Dec 1;197(11):4228-4239
1	J:310617 Gonzalez-Martinez J, Cwetsch AW, Martinez-Alonso D, Lopez-Sainz LR, Almagro J, Melati A, Gomez J, Perez-Martinez M, Megias D, Boskovic J, Gilabert-Juan J, Grana-Castro O, Pierani A, Behrens A, Ortega S, Malumbres M, Deficient adaptation to centrosome duplication defects in neural progenitors causes microcephaly and subcortical heterotopias. JCI Insight. 2021 Aug 23;6(16)
1*	J:248980 Guo H, Kazadaeva Y, Ortega FE, Manjunath N, Desai TJ, Trinucleotide repeat containing 6c (TNRC6c) is essential for microvascular maturation during distal airspace sacculation in the developing lung. Dev Biol. 2017 Oct 1;430(1):214-223
1	J:270164 Guo M, Du Y, Gokey JJ, Ray S, Bell SM, Adam M, Sudha P, Perl AK, Deshmukh H, Potter SS, Whitsett JA, Xu Y, Single cell RNA analysis identifies cellular heterogeneity and adaptive responses of the lung at birth. Nat Commun. 2019 Jan 3;10(1):37
1	J:197815 Hashimoto S, Chen H, Que J, Brockway BL, Drake JA, Snyder JC, Randell SH, Stripp BR, beta-Catenin-SOX2 signaling regulates the fate of developing airway epithelium. J Cell Sci. 2012 Feb 15;125(Pt 4):932-42
1	J:310843 He H, Chen J, Zhao J, Zhang P, Qiao Y, Wan H, Wang J, Mei M, Bao S, Li Q, PRMT7 targets of Foxm1 controls alveolar myofibroblast proliferation and differentiation during alveologenesis. Cell Death Dis. 2021 Sep 8;12(9):841
1*	J:306246 He M, Wu B, Ye W, Le DD, Sinclair AW, Padovano V, Chen Y, Li KX, Sit R, Tan M, Caplan MJ, Neff N, Jan YN, Darmanis S, Jan LY, Chloride channels regulate differentiation and barrier functions of the mammalian airway. Elife. 2020 Apr 14;9:e53085
1*	J:243650 Herriges MJ, Tischfield DJ, Cui Z, Morley MP, Han Y, Babu A, Li S, Lu M, Cendan I, Garcia BA, Anderson SA, Morrisey EE, The NANCI-Nkx2.1 gene duplex buffers Nkx2.1 expression to maintain lung development and homeostasis. Genes Dev. 2017 May 01;31(9):889-903
1	J:203056 Hines EA, Jones MK, Verheyden JM, Harvey JF, Sun X, Establishment of smooth muscle and cartilage juxtaposition in the developing mouse upper airways. Proc Natl Acad Sci U S A. 2013 Nov 26;110(48):19444-9
1	J:232894 Hrycaj SM, Dye BR, Baker NC, Larsen BM, Burke AC, Spence JR, Wellik DM, Hox5 Genes Regulate the Wnt2/2b-Bmp4-Signaling Axis during Lung Development. Cell Rep. 2015 Aug 11;12(6):903-12
1	J:87186 Huang T, You Y, Spoor MS, Richer EJ, Kudva VV, Paige RC, Seiler MP, Liebler JM, Zabner J, Plopper CG, Brody SL, Foxj1 is required for apical localization of ezrin in airway epithelial cells. J Cell Sci. 2003 Dec 15;116(Pt 24):4935-45
1*	J:65419 Ito T, Kagoshima M, Sasaki Y, Li C, Udaka N, Kitsukawa T, Fujisawa H, Taniguchi M, Yagi T, Kitamura H, Goshima Y, Repulsive axon guidance molecule Sema3A inhibits branching morphogenesis of fetal mouse lung. Mech Dev. 2000 Oct;97(1-2):35-45
1	J:135241 Izvolsky KI, Lu J, Martin G, Albrecht KH, Cardoso WV, Systemic inactivation of Hs6st1 in mice is associated with late postnatal mortality without major defects in organogenesis. Genesis. 2008 Jan;46(1):8-18
1*	J:255081 Jamsai D, Watkins DN, O'Connor AE, Merriner DJ, Gursoy S, Bird AD, Kumar B, Miller A, Cole TJ, Jenkins BJ, O'Bryan MK, In vivo evidence that RBM5 is a tumour suppressor in the lung. Sci Rep. 2017 Nov 24;7(1):16323
1	J:117367 Jay PY, Bielinska M, Erlich JM, Mannisto S, Pu WT, Heikinheimo M, Wilson DB, Impaired mesenchymal cell function in Gata4 mutant mice leads to diaphragmatic hernias and primary lung defects. Dev Biol. 2007 Jan 15;301(2):602-614
1	J:321004 Jiang M, Fang Y, Li Y, Huang H, Wei Z, Gao X, Sung HK, Hu J, Qiang L, Ruan J, Chen Q, Jiang D, Whitsett JA, Ai X, Que J, VEGF receptor 2 (KDR) protects airways from mucus metaplasia through a Sox9-dependent pathway. Dev Cell. 2021 Jun 7;56(11):1646-1660.e5
1	J:306030 Jiang M, Roth MG, Chun-On P, Sullivan DI, Alder JK, Phenotypic Diversity Caused by Differential Expression of SFTPC-Cre-Transgenic Alleles. Am J Respir Cell Mol Biol. 2020 Jun;62(6):692-698
1*	J:153715 Jin N, Cho SN, Raso MG, Wistuba I, Smith Y, Yang Y, Kurie JM, Yen R, Evans CM, Ludwig T, Jeong JW, DeMayo FJ, Mig-6 is required for appropriate lung development and to ensure normal adult lung homeostasis. Development. 2009 Oct;136(19):3347-56
1*	J:266596 Kersbergen A, Best SA, Dworkin S, Ah-Cann C, de Vries ME, Asselin-Labat ML, Ritchie ME, Jane SM, Sutherland KD, Lung morphogenesis is orchestrated through Grainyhead-like 2 (Grhl2) transcriptional programs. Dev Biol. 2018 Nov 1;443(1):1-9
1	J:268349 Kim HT, Yin W, Jin YJ, Panza P, Gunawan F, Grohmann B, Buettner C, Sokol AM, Preussner J, Guenther S, Kostin S, Ruppert C, Bhagwat AM, Ma X, Graumann J, Looso M, Guenther A, Adelstein RS, Offermanns S, Stainier DYR, Myh10 deficiency leads to defective extracellular matrix remodeling and pulmonary disease. Nat Commun. 2018 Nov 2;9(1):4600
1	J:282804 Kim HT, Yin W, Nakamichi Y, Panza P, Grohmann B, Buettner C, Guenther S, Ruppert C, Kobayashi Y, Guenther A, Stainier DYR, WNT/RYK signaling restricts goblet cell differentiation during lung development and repair. Proc Natl Acad Sci U S A. 2019 Dec 17;116(51):25697-25706
1	J:318015 Lange AW, Sridharan A, Xu Y, Stripp BR, Perl AK, Whitsett JA, Hippo/Yap signaling controls epithelial progenitor cell proliferation and differentiation in the embryonic and adult lung. J Mol Cell Biol. 2015 Feb;7(1):35-47
1	J:162039 Lee KS, Lee YS, Lee JM, Ito K, Cinghu S, Kim JH, Jang JW, Li YH, Goh YM, Chi XZ, Wee H, Lee HW, Hosoya A, Chung JH, Jang JJ, Kundu JK, Surh YJ, Kim WJ, Ito Y, Jung HS, Bae SC, Runx3 is required for the differentiation of lung epithelial cells and suppression of lung cancer. Oncogene. 2010 Jun 10;29(23):3349-61
1	J:178303 Lee Y, Fryer JD, Kang H, Crespo-Barreto J, Bowman AB, Gao Y, Kahle JJ, Hong JS, Kheradmand F, Orr HT, Finegold MJ, Zoghbi HY, ATXN1 protein family and CIC regulate extracellular matrix remodeling and lung alveolarization. Dev Cell. 2011 Oct 18;21(4):746-57
1	J:162871 Li A, Xing Y, Chan B, Heisterkamp N, Groffen J, Borok Z, Minoo P, Li C, Cell type-specific expression of adenomatous polyposis coli in lung development, injury, and repair. Dev Dyn. 2010 Aug;239(8):2288-97
1	J:136676 Li H, Cho SN, Evans CM, Dickey BF, Jeong JW, DeMayo FJ, Cre-mediated recombination in mouse Clara cells. Genesis. 2008 Jun;46(6):300-7
1	J:228600 Li Q, Wang HY, Chepelev I, Zhu Q, Wei G, Zhao K, Wang RF, Stage-dependent and locus-specific role of histone demethylase Jumonji D3 (JMJD3) in the embryonic stages of lung development. PLoS Genet. 2014 Jul;10(7):e1004524
1*	J:327630 Li R, Cai Y, Lin H, Dong L, Tang M, Lang Y, Qi Y, Peng Y, Zhou B, Yang G, Teng Y, Yang X, Generation of an Ihh-mKate2-Dre knock-in mouse line. Genesis. 2022 Jul;60(6-7):e23488
1	J:185603 Li S, Wang Y, Zhang Y, Lu MM, Demayo FJ, Dekker JD, Tucker PW, Morrisey EE, Foxp1/4 control epithelial cell fate during lung development and regeneration through regulation of anterior gradient 2. Development. 2012 Jul;139(14):2500-9
1*	J:171626 Li S, Xiang M, Foxn4 influences alveologenesis during lung development. Dev Dyn. 2011 Jun;240(6):1512-7
1*	J:224948 Lin C, Yao E, Chuang PT, A conserved MST1/2-YAP axis mediates Hippo signaling during lung growth. Dev Biol. 2015 Jul 1;403(1):101-13
1	J:277670 Liu J, Zhou Y, Liu Y, Li L, Chen Y, Liu Y, Feng Y, Yosypiv IV, Song R, Peng H, (Pro)renin receptor regulates lung development via the Wnt/beta-catenin signaling pathway. Am J Physiol Lung Cell Mol Physiol. 2019 Aug 1;317(2):L202-L211
1	J:221734 Liu S, Young SM, Varisco BM, Dynamic expression of chymotrypsin-like elastase 1 over the course of murine lung development. Am J Physiol Lung Cell Mol Physiol. 2014 Jun 15;306(12):L1104-16
1	J:241923 Lopez IP, Pineiro-Hermida S, Pais RS, Torrens R, Hoeflich A, Pichel JG, Involvement of Igf1r in Bronchiolar Epithelial Regeneration: Role during Repair Kinetics after Selective Club Cell Ablation. PLoS One. 2016;11(11):e0166388
1	J:166685 Love D, Li FQ, Burke MC, Cyge B, Ohmitsu M, Cabello J, Larson JE, Brody SL, Cohen JC, Takemaru K, Altered lung morphogenesis, epithelial cell differentiation and mechanics in mice deficient in the Wnt/beta-catenin antagonist Chibby. PLoS One. 2010;5(10):e13600
1*	J:128019 Lu Y, Thomson JM, Wong HY, Hammond SM, Hogan BL, Transgenic over-expression of the microRNA miR-17-92 cluster promotes proliferation and inhibits differentiation of lung epithelial progenitor cells. Dev Biol. 2007 Oct 15;310(2):442-53
1	J:195172 Ludtke TH, Farin HF, Rudat C, Schuster-Gossler K, Petry M, Barnett P, Christoffels VM, Kispert A, Tbx2 controls lung growth by direct repression of the cell cycle inhibitor genes Cdkn1a and Cdkn1b. PLoS Genet. 2013 Jan;9(1):e1003189
1*	J:179954 Matsumoto S, Konishi H, Maeda R, Kiryu-Seo S, Kiyama H, Expression analysis of the regenerating gene (Reg) family members Reg-IIIbeta and Reg-IIIgamma in the mouse during development. J Comp Neurol. 2012 Feb 15;520(3):479-94
1	J:158087 McPherson JP, Sarras H, Lemmers B, Tamblyn L, Migon E, Matysiak-Zablocki E, Hakem A, Azami SA, Cardoso R, Fish J, Sanchez O, Post M, Hakem R, Essential role for Bclaf1 in lung development and immune system function. Cell Death Differ. 2009 Feb;16(2):331-9
1	J:156690 Morimoto M, Liu Z, Cheng HT, Winters N, Bader D, Kopan R, Canonical Notch signaling in the developing lung is required for determination of arterial smooth muscle cells and selection of Clara versus ciliated cell fate. J Cell Sci. 2010 Jan 15;123(Pt 2):213-24
1*	J:276140 Naizhen X, Kido T, Yokoyama S, Linnoila RI, Kimura S, Spatiotemporal Expression of Three Secretoglobin Proteins, SCGB1A1, SCGB3A1, and SCGB3A2, in Mouse Airway Epithelia. J Histochem Cytochem. 2019 Jun;67(6):453-463
1	J:282576 Nakajima K, Ono M, Radovic U, Dizdarevic S, Tomizawa SI, Kuroha K, Nagamatsu G, Hoshi I, Matsunaga R, Shirakawa T, Kurosawa T, Miyazaki Y, Seki M, Suzuki Y, Koseki H, Nakamura M, Suda T, Ohbo K, Lack of whey acidic protein (WAP) four-disulfide core domain protease inhibitor 2 (WFDC2) causes neonatal death from respiratory failure in mice. Dis Model Mech. 2019 Nov 12;12(11):dmm040139
1*	J:196288 Nechiporuk T, Klezovitch O, Nguyen L, Vasioukhin V, Dlg5 maintains apical aPKC and regulates progenitor differentiation during lung morphogenesis. Dev Biol. 2013 May 15;377(2):375-84
1*	J:72388 Niimi T, Keck-Waggoner CL, Popescu NC, Zhou Y, Levitt RC, Kimura S, UGRP1, a Uteroglobin/Clara Cell Secretory Protein-Related Protein, Is a Novel Lung-Enriched Downstream Target Gene for the T/EBP/NKX2.1 Homeodomain Transcription Factor. Mol Endocrinol. 2001 Nov;15(11):2021-36
1	J:183999 Ouseph MM, Li J, Chen HZ, Pecot T, Wenzel P, Thompson JC, Comstock G, Chokshi V, Byrne M, Forde B, Chong JL, Huang K, Machiraju R, de Bruin A, Leone G, Atypical E2F repressors and activators coordinate placental development. Dev Cell. 2012 Apr 17;22(4):849-62
1	J:242076 Poobalasingam T, Yates LL, Walker SA, Pereira M, Gross NY, Ali A, Kolatsi-Joannou M, Jarvelin MR, Pekkanen J, Papakrivopoulou E, Long DA, Griffiths M, Wagner D, Konigshoff M, Hind M, Minelli C, Lloyd CM, Dean CH, Heterozygous Vangl2Looptail mice reveal novel roles for the planar cell polarity pathway in adult lung homeostasis and repair. Dis Model Mech. 2017 Apr 01;10(4):409-423
1	J:175564 Porter JL, Bukey BR, Geyer AJ, Willnauer CP, Reynolds PR, Immunohistochemical detection and regulation of alpha5 nicotinic acetylcholine receptor (nAChR) subunits by FoxA2 during mouse lung organogenesis. Respir Res. 2011;12:82
1	J:333735 Qi H, Liu H, Pullamsetti SS, Gunther S, Kuenne C, Atzberger A, Sommer N, Hadzic S, Gunther A, Weissmann N, Zhou Y, Yuan X, Braun T, Epigenetic Regulation by Suv4-20h1 in Cardiopulmonary Progenitor Cells Is Required to Prevent Pulmonary Hypertension and Chronic Obstructive Pulmonary Disease. Circulation. 2021 Sep 28;144(13):1042-1058
1	J:34630 Ray MK, Wang G, Barrish J, Finegold MJ, DeMayo FJ, Immunohistochemical localization of mouse Clara cell 10-KD protein using antibodies raised against the recombinant protein. J Histochem Cytochem. 1996 Aug;44(8):919-27
1*	J:170419 Reynolds PR, Allison CH, Willnauer CP, TTF-1 regulates alpha5 nicotinic acetylcholine receptor (nAChR) subunits in proximal and distal lung epithelium. Respir Res. 2010;11:175
1	J:101308 Reynolds PR, Hoidal JR, Temporal-spatial expression and transcriptional regulation of alpha7 nicotinic acetylcholine receptor by thyroid transcription factor-1 and early growth response factor-1 during murine lung development. J Biol Chem. 2005 Sep 16;280(37):32548-54
1	J:185114 Reynolds SD, Zemke AC, Giangreco A, Brockway BL, Teisanu RM, Drake JA, Mariani T, Di PY, Taketo MM, Stripp BR, Conditional stabilization of beta-catenin expands the pool of lung stem cells. Stem Cells. 2008 May;26(5):1337-46
1*	J:138613 Rock JR, Futtner CR, Harfe BD, The transmembrane protein TMEM16A is required for normal development of the murine trachea. Dev Biol. 2008 Sep 1;321(1):141-9
1*	J:323339 Salwig I, Spitznagel B, Vazquez-Armendariz AI, Khalooghi K, Guenther S, Herold S, Szibor M, Braun T, Bronchioalveolar stem cells are a main source for regeneration of distal lung epithelia in vivo. EMBO J. 2019 Jun 17;38(12):e102099
1	J:198319 Sayin VI, Nilton A, Ibrahim MX, Agren P, Larsson E, Petit MM, Hulten LM, Stahlman M, Johansson BR, Bergo MO, Lindahl P, Zfp148 deficiency causes lung maturation defects and lethality in newborn mice that are rescued by deletion of p53 or antioxidant treatment. PLoS One. 2013;8(2):e55720
1	J:338817 Schoultz E, Liang S, Carlsson T, Filges S, Stahlberg A, Fagman H, Wiel C, Sayin V, Nilsson M, Tissue specificity of oncogenic BRAF targeted to lung and thyroid through a shared lineage factor. iScience. 2023 Jul 21;26(7):107071
1	J:137729 Schuhmacher AJ, Guerra C, Sauzeau V, Canamero M, Bustelo XR, Barbacid M, A mouse model for Costello syndrome reveals an Ang II-mediated hypertensive condition. J Clin Invest. 2008 Jun;118(6):2169-79
1	J:217677 Snitow ME, Li S, Morley MP, Rathi K, Lu MM, Kadzik RS, Stewart KM, Morrisey EE, Ezh2 represses the basal cell lineage during lung endoderm development. Development. 2015 Jan 1;142(1):108-17
1	J:132011 Sun J, Chen H, Chen C, Whitsett JA, Mishina Y, Bringas P Jr, Ma JC, Warburton D, Shi W, Prenatal lung epithelial cell-specific abrogation of alk3-bone morphogenetic protein signaling causes neonatal respiratory distress by disrupting distal airway formation. Am J Pathol. 2008 Mar;172(3):571-82
1	J:284174 Swarr DT, Herriges M, Li S, Morley M, Fernandes S, Sridharan A, Zhou S, Garcia BA, Stewart K, Morrisey EE, The long noncoding RNA Falcor regulates Foxa2 expression to maintain lung epithelial homeostasis and promote regeneration. Genes Dev. 2019 Jun 1;33(11-12):656-668
1	J:156253 Tateossian H, Hardisty-Hughes RE, Morse S, Romero MR, Hilton H, Dean C, Brown SD, Regulation of TGF-beta signalling by Fbxo11, the gene mutated in the Jeff otitis media mouse mutant. Pathogenetics. 2009;2(1):5
1	J:115581 Tian J, Mahmood R, Hnasko R, Locker J, Loss of Nkx2.8 deregulates progenitor cells in the large airways and leads to dysplasia. Cancer Res. 2006 Nov 1;66(21):10399-407
1	J:55155 Tichelaar JW, Wert SE, Costa RH, Kimura S, Whitsett JA, HNF-3/forkhead homologue-4 (HFH-4) is expressed in ciliated epithelial cells in the developing mouse lung. J Histochem Cytochem. 1999 Jun;47(6):823-32
1	J:167962 Tiozzo C, De Langhe S, Yu M, Londhe VA, Carraro G, Li M, Li C, Xing Y, Anderson S, Borok Z, Bellusci S, Minoo P, Deletion of Pten expands lung epithelial progenitor pools and confers resistance to airway injury. Am J Respir Crit Care Med. 2009 Oct 15;180(8):701-12
1	J:234401 Tsao PN, Matsuoka C, Wei SC, Sato A, Sato S, Hasegawa K, Chen HK, Ling TY, Mori M, Cardoso WV, Morimoto M, Epithelial Notch signaling regulates lung alveolar morphogenesis and airway epithelial integrity. Proc Natl Acad Sci U S A. 2016 Jul 19;113(29):8242-7
1	J:150051 Tsao PN, Vasconcelos M, Izvolsky KI, Qian J, Lu J, Cardoso WV, Notch signaling controls the balance of ciliated and secretory cell fates in developing airways. Development. 2009 Jul;136(13):2297-307
1	J:175774 Tsao PN, Wei SC, Wu MF, Huang MT, Lin HY, Lee MC, Lin KM, Wang IJ, Kaartinen V, Yang LT, Cardoso WV, Notch signaling prevents mucous metaplasia in mouse conducting airways during postnatal development. Development. 2011 Aug;138(16):3533-43
1	J:266598 Ustiyan V, Bolte C, Zhang Y, Han L, Xu Y, Yutzey KE, Zorn AM, Kalin TV, Shannon JM, Kalinichenko VV, FOXF1 transcription factor promotes lung morphogenesis by inducing cellular proliferation in fetal lung mesenchyme. Dev Biol. 2018 Nov 1;443(1):50-63
1	J:272593 Volckaert T, Yuan T, Yuan J, Boateng E, Hopkins S, Zhang JS, Thannickal VJ, Fassler R, De Langhe SP, Hippo signaling promotes lung epithelial lineage commitment by curbing Fgf10 and beta-catenin signaling. Development. 2019 Jan 16;146(2):dev166454
1	J:84053 Wang T, Tamakoshi T, Uezato T, Shu F, Kanzaki-Kato N, Fu Y, Koseki H, Yoshida N, Sugiyama T, Miura N, Forkhead transcription factor Foxf2 (LUN)-deficient mice exhibit abnormal development of secondary palate. Dev Biol. 2003 Jul 1;259(1):83-94
1	J:195044 Wang Y, Tian Y, Morley MP, Lu MM, Demayo FJ, Olson EN, Morrisey EE, Development and regeneration of Sox2+ endoderm progenitors are regulated by a Hdac1/2-Bmp4/Rb1 regulatory pathway. Dev Cell. 2013 Feb 25;24(4):345-58
1	J:211804 Woik N, Dietz CT, Schaker K, Kroll J, Kelch-like ECT2-interacting protein KLEIP regulates late-stage pulmonary maturation via Hif-2alpha in mice. Dis Model Mech. 2014 Jun;7(6):683-92
1*	J:282446 Woo AJ, Patry CA, Ghamari A, Pregernig G, Yuan D, Zheng K, Piers T, Hibbs M, Li J, Fidalgo M, Wang JY, Lee JH, Leedman PJ, Wang J, Fraenkel E, Cantor AB, Zfp281 (ZBP-99) plays a functionally redundant role with Zfp148 (ZBP-89) during erythroid development. Blood Adv. 2019 Aug 27;3(16):2499-2511
1	J:333558 Wu F, Li X, Looso M, Liu H, Ding D, Gunther S, Kuenne C, Liu S, Weissmann N, Boettger T, Atzberger A, Kolahian S, Renz H, Offermanns S, Gartner U, Potente M, Zhou Y, Yuan X, Braun T, Spurious transcription causing innate immune responses is prevented by 5-hydroxymethylcytosine. Nat Genet. 2023 Jan;55(1):100-111
1	J:190179 Xing Y, Li A, Borok Z, Li C, Minoo P, NOTCH1 is required for regeneration of Clara cells during repair of airway injury. Stem Cells. 2012 May;30(5):946-55
1	J:157922 Xing Y, Li C, Li A, Sridurongrit S, Tiozzo C, Bellusci S, Borok Z, Kaartinen V, Minoo P, Signaling via Alk5 controls the ontogeny of lung Clara cells. Development. 2010 Mar;137(5):825-33
1	J:323100 Xu J, Xu L, Sui P, Chen J, Moya EA, Hume P, Janssen WJ, Duran JM, Thistlethwaite P, Carlin A, Gulleman P, Banaschewski B, Goldy MK, Yuan JX, Malhotra A, Pryhuber G, Crotty-Alexander L, Deutsch G, Young LR, Sun X, Excess neuropeptides in lung signal through endothelial cells to impair gas exchange. Dev Cell. 2022 Apr 11;57(7):839-853.e6
1	J:247907 Yao J, Guihard PJ, Wu X, Blazquez-Medela AM, Spencer MJ, Jumabay M, Tontonoz P, Fogelman AM, Bostrom KI, Yao Y, Vascular endothelium plays a key role in directing pulmonary epithelial cell differentiation. J Cell Biol. 2017 Oct 02;216(10):3369-3385
1	J:296772 Yin W, Kim HT, Wang S, Gunawan F, Li R, Buettner C, Grohmann B, Sengle G, Sinner D, Offermanns S, Stainier DYR, Fibrillin-2 is a key mediator of smooth muscle extracellular matrix homeostasis during mouse tracheal tubulogenesis. Eur Respir J. 2019 Mar;53(3)
1	J:266389 Yin W, Kim HT, Wang S, Gunawan F, Wang L, Kishimoto K, Zhong H, Roman D, Preussner J, Guenther S, Graef V, Buettner C, Grohmann B, Looso M, Morimoto M, Mardon G, Offermanns S, Stainier DYR, The potassium channel KCNJ13 is essential for smooth muscle cytoskeletal organization during mouse tracheal tubulogenesis. Nat Commun. 2018 Jul 19;9(1):2815
1	J:321577 Yin W, Liontos A, Koepke J, Ghoul M, Mazzocchi L, Liu X, Lu C, Wu H, Fysikopoulos A, Sountoulidis A, Seeger W, Ruppert C, Gunther A, Stainier DYR, Samakovlis C, An essential function for autocrine hedgehog signaling in epithelial proliferation and differentiation in the trachea. Development. 2022 Feb 1;149(3):dev199804
1	J:182350 Zanucco E, Gotz R, Potapenko T, Carraretto I, Ceteci S, Ceteci F, Seeger W, Savai R, Rapp UR, Expression of B-RAF V600E in type II pneumocytes causes abnormalities in alveolar formation, airspace enlargement and tumor formation in mice. PLoS One. 2011;6(12):e29093
1	J:157431 Zemke AC, Snyder JC, Brockway BL, Drake JA, Reynolds SD, Kaminski N, Stripp BR, Molecular staging of epithelial maturation using secretory cell-specific genes as markers. Am J Respir Cell Mol Biol. 2009 Mar;40(3):340-8
1	J:332095 Zhang K, Yao E, Chuang E, Chen B, Chuang EY, Chuang PT, mTORC1 signaling facilitates differential stem cell differentiation to shape the developing murine lung and is associated with mitochondrial capacity. Nat Commun. 2022 Nov 25;13(1):7252
1*	J:314587 Zhang S, Dai H, Li W, Wang R, Wu H, Shen M, Hu Y, Xie L, Xing Y, TMEM116 is required for lung cancer cell motility and metastasis through PDK1 signaling pathway. Cell Death Dis. 2021 Nov 16;12(12):1086
1*	J:35560 Zhou L, Lim L, Costa RH, Whitsett JA, Thyroid transcription factor-1, hepatocyte nuclear factor-3beta, surfactant protein B, C, and Clara cell secretory protein in developing mouse lung. J Histochem Cytochem. 1996 Oct;44(10):1183-93
1	J:144215 Zhu L, Gibson P, Currle DS, Tong Y, Richardson RJ, Bayazitov IT, Poppleton H, Zakharenko S, Ellison DW, Gilbertson RJ, Prominin 1 marks intestinal stem cells that are susceptible to neoplastic transformation. Nature. 2009 Jan 29;457(7229):603-7
1	J:168607 Zielonka M, Xia J, Friedel RH, Offermanns S, Worzfeld T, A systematic expression analysis implicates Plexin-B2 and its ligand Sema4C in the regulation of the vascular and endocrine system. Exp Cell Res. 2010 Sep 10;316(15):2477-86